Research - Laboratory/Non-Laboratory, Staff/Administrative
Summary of Position:
This individual will be responsible for conducting a variety of techniques in animal experimentation and molecular biology. The individual will also participate in mouse colony organization and maintenance, using our laboratory’s mouse cloud database to create specimen labels, archiving biological samples, and supply ordering. This individual will also perform molecular biology techniques including genotyping, tissue culture, animal dosing, physiologic measurements, necropsies, tissue preservation, shipment of biological samples and recording healthspan data in the database. Continuing self-motivated education in aging research is expected.
Lab Research Summary:
Our research program is focused on investigating the underlying causes of aging. We use mouse models extensively, employing both genetic and pharmacologic approaches to interrogate mechanisms of aging. Aging is investigated in vivo by measuring senescence, frailty, organ function and behavior. The candidate will join an exciting research environment in the Department of Biochemistry, Molecular Biology, and Biophysics and the Institute on the Biology of Aging and Metabolism at the University of Minnesota Twin Cities. The position offers exceptional training in animal physiology, aging, age-related disease and pre-clinical testing of drugs.
50% Animal husbandry, mouse colony management, collect and record data collected on live animals, mouse necropsies, collection and preservation of biological samples. Employee will be responsible for the collection and analysis of data, including statistical significance, using Excel, GraphPad Prism and other applicable software
25% Use the lab’s unique colony management database, create animal identifiers and cage cards, prepare necropsy reports and labels for biologic samples, archive samples in the tissue bank and ship biological samples to collaborators.
25% Prepare tissue lysates, isolation of genomic DNA, genotyping, nucleic acid and protein electrophoresis and tissue culture.
All required qualifications must be documented on application materials.
Required Qualifications: BS/BA in biomedical discipline and at least one year of experience working with aged mice, or a combination of related education and work experience to equal to at least five years. Experience with maintaining animal colonies, physiologic endpoint measurement and dosing of animals. Must have strong data management and problem solving skills, an ability to multitask and to work independently.
Applicants should have an interest in health sciences and interest in working with laboratory animals. Experience with RNA isolation, qPCR, and tissue culture is preferred.
Internal Number: 335255
About University of Minnesota, Twin Cities
The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.