Research - Laboratory/Non-Laboratory, Staff/Administrative
Applications are invited for a Postdoctoral Research Fellowship in the University of Minnesota Physical Sciences in Oncology Center (“PSOC”). The successful applicant will be co-advised by Drs. David Odde and Paolo Provenzano on a project using an integrated experimental and computational modeling approach to study cancer and T-cell migration in Pancreatic Ductal Adenocarcinoma (“PDA”) and Glioblastoma (“GBM”).
Dr. Odde is the Principal Investigator or the UMN PSOC which is a collaborative effort engaging many labs across the University of Minnesota as well as the Mayo Clinic and with other PSOC centers across the country. Dr. Provenzano is a PSOC project PI.
Position: Primary work will be to develop a computational simulator of PDA tumor and immune cell migration dynamics that integrates sophisticated microenvironmental parameters. This work will build on the Odde lab’s GBM Cell Migration Simulator and the Provenzano lab’s expertise in PDA biophysics. This work includes coding, protocol development and implementation, including tissue/cell processing, live cell imaging by light microscopy, and digital image analysis. The work will be performed collaboratively with clinicians, including neurosurgeons and neuro- and GI-oncologists, and with theorists, including biomedical engineers engaged in computational modeling of cellular dynamics such as cell migration.
Computational modeling – 40%
Live cell imaging and associated tissue/cell processing – 40%
Data analysis and manuscript writing – 20%
Ph.D. in biomedical, chemical, or mechanical engineering
Strong computer programming skills (especially cross-platform C++ and/or Matlab).
Demonstrated research productivity
Expertise in mammalian cell culture, live cell imaging via fluorescence and transmitted light microscopy, cloning, gel electrophoresis, DNA & RNA purification, and statistical analysis of data.
Internal Number: 332580
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